The topic you choose must have enough depth that you can create a lot of content for it. This is important for building an authoritative site, for search engine optimization, and most importantly, for the end user. If you don't have enough content about a topic, you're not going to be taken very seriously as an authority on the topic and it's unlikely you can convince someone to make a purchase from you.
Creating a video series and selling it as a digital download on your blog, much like an eBook, can be another great seller. A video course, teaching viewers a specific skill or how to achieve a particular activity, may well resonate with your audience. If you are going to go down this route then your videos need to be as professional as possible so you should consider investing in some video and lighting equipment, as well as editing software.
The phrase, "Affiliates are an extended sales force for your business", which is often used to explain affiliate marketing, is not completely accurate. The primary difference between the two is that affiliate marketers provide little if any influence on a possible prospect in the conversion process once that prospect is directed to the advertiser's website. The sales team of the advertiser, however, does have the control and influence up to the point where the prospect either a) signs the contract, or b) completes the purchase.
Running a coupons website can be very lucrative. Find a coupon niche, select a WordPress coupon theme, and then display relevant coupons on your site. When your audience uses the coupon codes or discount links, you will earn an affiliate cut for example you could set-up a site dedicated to iHerb Coupons or add a page to your website with Web Hosting Promo Codes. Coupon websites are quite high maintenance as they need to be constantly updated with new offers. However, if you build up an engaged audience and allow them to post coupons and discounts they have found themselves, then quite quickly your workload will reduce.